Fig. 4

BM prediction of the measured HSL-dependent RFP output in all the test set circuits with Monitor cassette. Circles represent the average measured value and error bars represent the 95% confidence intervals of the mean. Solid line represents the median predicted output of the model calculated via Monte Carlo simulations for each HSL concentration tested. Dashed dark red lines are the 95% confidence bands of the output distribution. Dashed light red lines are the 95% confidence bands of the output distribution calculated after multivariate sensitivity analysis