Fig. 8

Pancreatic protein expression and functional analyses of encapsulated hDPSC-IPCs using ALG and ALGPA. The expression of pro-insulin and insulin by ALG- and ALGPA-encapsulated hDPSC-IPCs were evaluated by immunocytochemistry staining at day 7 and 14 post-encapsulation a. C-peptide secretion was also determined by glucose-stimulated C-peptide secretion (GSCS) assay b. The asterisks indicated significant difference, comparing with normal and glucose 5.5 mM in KRBH (p < 0.05)