Fig. 2

Fabrication of PLA-Exo scaffold. A The view of the 3D printed PLA scaffold. B Representative imaging of PLA scaffold modified with PKH26-labeled exosomes. C Fluorescent imaging of exosomes released from PLA-Exo scaffold into Raw 264.7 cells. Cells were stained with phalloidin (green), nucleus (blue), and examined by a confocal laser scanning microscopy. D Uptake of exosomes released from PLA-Exo scaffold by hBMSCs. Exosomes were prelabeled with PKH26. The internalization of the exosomes released from scaffold was evaluated by a confocal laser scanning microscopy