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Fig. 4 | Journal of Biological Engineering

Fig. 4

From: Development of anti-aflatoxin B1 nanobodies from a novel mutagenesis-derived synthetic library for traditional Chinese medicine and foods safety testing

Fig. 4

Isolated nanobodies can neutralize AFB1-induced hepatocyte growth inhibition by binding to AFB1. A The growth inhibitory effect of AFB1 at multiple concentrations in CL48 normal human liver cells and HepG2.2.15 human hepatoblastoma cells was measured after 48 h of treatment. B Nanobodies A1 (nb A1) and F2 (nb F2) interacted with AFB1 at a specified concentration; the protective effect on cell growth was monitored after treating HepG2.2.15 cells with AFB1 for 48 h; ***P < 0.001. An irrelevant nanobody (nb NC) that did not recognize AFB1 was used as the negative control

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Journal of Biological Engineering

ISSN: 1754-1611