Fig. 7
From: Breast cancer brain metastasis: from etiology to state-of-the-art modeling
A Representative microscopic images demonstrating transendothelial migration on the Transwell® as well as BBB cell penetration on chip (upper and lower scale bar are 20 and 50 μm, respectively). B Time-lapse microscopic photos were taken over 72 h show the movement of a variety of cancer cells through the BBB system. Diagrams depicting the movement of different cancer cells pass through the BBB. Reprinted in part with permission from refs [239, 240]