Fig. 1

Schematic diagram of the coating procedure. The ability of dopamine to deposit on multiple substrates through self-polymerization is the foundation of the universality of the coating method developed in this study (panel a). After removal of the protective t-boc group, hydrazides in the linker react with aldehydes created by oxidation of cis-diols in the polysaccharide moieties of Fc region (panel b), resulting in oriented antibody coating (panel c)