Fig. 5
From: Proteomic analysis of decellularized mice liver and kidney extracellular matrices
Biochemical analysis of decellularized matrices. Collagen (A) and sGAG (B) content was quantified for decellularized liver (dLM) and kidney (dKM) matrices compared to native tissues (nLM and nKM). The amount of collagen in µg per mg of wet tissue was significantly higher in the decellularized tissue of both organs (dLM: 1.82 ± 1.84 µg/mg, nLM: 0.19 ± 0.09 µg/ mg (*** p < 0.0001); dKM: 7.37 ± 8.37 µg/mg, nKM: 1.34 ± 1.06 µg/mg (*** p < 0.0001)). The sGAG content in ng per mg of wet tissue showed no statistically significant difference between the decellularized and native samples (dLM: 92.60 ± 65.37 ng/mg, nLM: 171.92 ± 50.65 ng/mg (p > 0.05); dKM: 102.30 ± 80.05 ng/mg, nKM: 155.30 ± 73.24 ng/mg (p > 0.05)). Nevertheless, a trend in favor of the native tissue was observed