Fig. 9

a Representative extracted negative ion MRM chromatograms of organic acids at the MQC: glutamic acid (m/z: 145.96/128.0, RT: 5.13Â min), gluconic acid (m/z: 194.95/129.1, RT: 5.59Â min), succinic acid (m/z: 116.88/72.9, RT: 5.60Â min), lactic acid (m/z: 88.62/43.0, RT: 5.61Â min), citric acid (m/z: 190.92/111.0, RT: 5.75Â min), tartaric acid (m/z: 148.69/87, RT: 5.77Â min), pyruvic acid (m/z: 86.94/43.0, RT: 6.12Â min), salicylic acid (m/z: 136.94/93.0, RT: 6.63Â min), and maleic acid (m/z: 114.91/71.0, RT: 6.85Â min). b Monitoring of biomass, lactic, gluconic, glutamic, and citric acids production; c Monitoring of biomass, succinic, salicylic, malic, and tartaric acids production throughout shake-flask cultivation system; d Representative extracted negative ion MRM chromatograms illustrating the presence of hydroxybenzoic acid alongside salicylic acid