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Fig. 5 | Journal of Biological Engineering

Fig. 5

From: Oxygenator assisted dynamic microphysiological culture elucidates the impact of hypoxia on valvular interstitial cell calcification

Fig. 5

Relative marker mRNA expression in dynamic vs. static MPS culture of hVICs in calcification induction media ADGM and PM. (A) Changes of expression in dynamic MPS culture comparing DMEM, ADGM and PM for marker genes ACTA2, FN1, RUNX2 and SOX9, (B) respective mRNA expression set in static MPS chip culture. (one-way ANOVA and Tukey-test or Friedmann and Dunn`s-test, respectively; *p < 0.05; **p < 0.01; # p < 0.1)

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Journal of Biological Engineering

ISSN: 1754-1611