Fig. 1

Differential gene and protein expression upon MSI-1* expression by RNA-seq and Ribo-seq. a Scatter plot of the expression of all host genes with and without MSI-1* (average of two replicates from RNA-seq). Transcriptionally up-regulated genes marked in red and transcriptionally down-regulated genes in blue. b Scatter plot of the fold change in RNA and protein expression (from RNA-seq and Ribo-seq, respectively) of all host genes upon MSI-1* expression (average of two replicates). Gene with up-regulated translation marked in red and gene with down-regulated translation in blue. c Functional analysis for the transcriptionally up-regulated genes. A relationship between gene proportion and adjusted P value is presented. d Functional analysis for the transcriptionally down-regulated genes