Fig. 2

Microglia lipid content increases upon activation with cytokines. (A) Overall cellular lipid content across different lipid classes increases following stimulation (+CTL). Lipid classes identified using negative mode (A) and positive mode (B) ionization. Each lipid species is significantly different between –CTL and +CTL (p<0.05) except LPC (denoted by ‘ns’) using unpaired t-test with Welch’s correction. (C) Pathways ordered by p-value significance (1-log10(p-val)) with significantly enriched pathways above red horizontal line at p-value cutoff = 0.05