Fig. 4

Venn diagram indicating the overlap between differentially expression genes (DEG) in SMCs receiving various glucose concentrations (10 mmol/L and 20 mmol/L). RNA-seq data for each condition was compared to cells receiving 5 mmol/L glucose. T2DM cells were also shown for comparison. (A) Up-regulated differentially expressed genes; (B) down-regulated differentially expressed genes. Cell pellets were pooled from n = 6 wells/ condition for RNA-seq analysis