Fig. 5

Observation of spheroid morphology and size distribution under static and pseudostatic culture methods after 14 days of cultivation. Bright field images in (a) show the morphological characteristics of cell spheroids in static dish cultures, while (c) illustrates those in a bioreactor system. The size distributions for the static and pseudostatic culture methods are presented in (b) and (d), respectively. Scale bar = 100 μm