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Fig. 6 | Journal of Biological Engineering

Fig. 6

From: Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration

Fig. 6

Analysis of inflammatory and osteogenic markers in samples with different lithium content over various culture times. (A) Concentration of interleukin-1 beta (IL-1β) on days one and three, (B) Concentration of interleukin-6 (IL-6) on days one and three, (C) concentration of interleukin-10 (IL-10) on days one and three, (D) relative activity of alkaline phosphatase (ALP) on days three and seven, and (E) concentration of osteocalcin (OC) on days 7 and 14. Data are presented as the means ± SEM; n = 6 for each group. The symbols “*” and “#” denote statistically significant differences (P < 0.05) between Li5 and Li0 and Li10 and Li0 groups, respectively

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