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Fig. 3 | Journal of Biological Engineering

Fig. 3

From: Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-term storage

Fig. 3

(a) TEM with manually measured mean, SD, and counts per frame (b) NTA particle distribution (mean {black bar}, mode {yellow marker}, STDEV {error bars}), calculated polydispersity index (PDI), and particle counts. Means were not statistically different via using multiple T tests with Bonferroni Correction (α = 0.05) (c) ECIS scratch-assay bioactivity for mEV samples stored for 1 month in various conditions in HEPES buffer. ECIS wound recovery was analyzed by multiple T tests with Bonferroni Correction (α = 0.05); statistically significant differences were noted between fresh mEVs and 20ºC (p = 0.001) and − 80ºC (p = 0.0001); N = 4

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Journal of Biological Engineering

ISSN: 1754-1611