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Fig. 5 | Journal of Biological Engineering

Fig. 5

From: Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-term storage

Fig. 5

(a) TEM images of lyophilized mEVs stored in 50mM TH and 50mM TH + 100µM Tryptophan (b) TEM images of lyophilized mEVs reconstituted in diH2O (c) NTA particle distribution. All group means were not statistically significant (Multiple T tests with Bonferroni Correction, α = 0.05) c) ECIS scratch-assay bioactivity for lyophilized mEV samples stored for 1 month at RT. Multiple T tests with Bonferroni Correction (α = 0.05) showed statistical significance between fresh mEV controls and 50mM TH + 100µM Tryptophan (p = 0.0048); N = 4 (d) DSC thermal stability of mEV powders N = 1, error bars represent standard error associated with calibration

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Journal of Biological Engineering

ISSN: 1754-1611