Fig. 4

Analyzing the integration of HAP in SA hydrogel through H-bond and SASA (A) SA molecule; (B) HAP molecule; (C) normalized H-bond analysis among HAP and SA-water; (D) averaged normalized H-bond analysis among HAP and water; (E) SASA analysis fluctuations of the 0, 10, 20, 30, and 40 wt% HAP in SA hydrogel composition; and (F) SASA distribution diagram of the 0, 10, 20, 30, and 40 wt% HAP in SA hydrogel composition. All the H-bond and SASA analyses confirmed that 10 wt% HAP has the best and optimal state over the simulation