Fig. 3
From: Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
Mutations at position 187 enhance ACE2 catalytic activity. (a) Catalytic activity of K187 mutants. Multiple amino acid substitutions at position 187 enhance ACE2 activity. Error bars represent one standard deviation for triplicate measurements. (b) Initial rate plots of ACE2 and K187Q/T mutants. The K187 mutants have increased kcat and decreased KM relative to wildtype (WT) ACE2