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Fig. 1 | Journal of Biological Engineering

Fig. 1

From: Rapid osteoinduction of human adipose-derived stem cells grown on bioactive surfaces and stimulated by chemically modified media flow

Fig. 1

Human ASC osteogenesis is supported by culture on SBG-PLGA composites and rhBMP-2 treatment. mRNA levels of the early and late osteoblastic markers, BMP-2 and Noggin (NOG) in human ASCs cultured on SBG-PLGA composites in (A), (C) standard osteogenic medium or (B), (D) standard osteogenic medium supplemented with 100 ng/ml rhBMP-2. Results are presented as relative mRNA expression levels vs. mRNA levels for ASCs cultured on a plain PLGA control (black line at 1). (E) Nitric oxide (NO) concentration in culture media after 24-h culture of ASC cells on SBG-PLGA composites in standard osteogenic medium. Averages ± SD are indicated. One-way or two-way ANOVA tests, *p < 0.05, **p < 0.001, ***p < 0.0001 relative to the PLGA control group

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Journal of Biological Engineering

ISSN: 1754-1611